Description
Why superNEB?

cGMP certified lab
superNEB is manufactured in a certified and regulatory standard for ensuring pharmaceutical quality, which ensures that our processes are safe and hygiene.

Non-chemical component
The medicine are derived from natural substance that had no adverse effect to our body but to help regulate the overall respiratory system.

Anti-inflammatory
superNEB induce anti-inflammatory properties such as IL-10 to promote immunomodulating effects and reduce hyperallergic reaction for patients with respiratory problem.

Enhance lung function
superNEB provide direct anti-microbial effects which helps to combat lung infection, this will also reduce apoptosis and improve lung function or breathlessness.

Regeneration
superNEB has the ability to promote cell-to-cell communication to induce phenotypic and functional changes in the recipient cells and promote the activation of regeneration.

Suitable for everyone
superNEB are non-invasive and non-chemical component which it is suitable for adult and children.
Suitable for anyone who are:

Post-covid patient

Patients with respiratory conditions

Allergic rhinitis

Smokers

Sleeping difficulties

Breathing difficulties
Credentials
The natural biological ingredient of superNEB is safe to be inhaled because it is produced in a cGMP certified laboratory with the following credentials:


superNEB Nebulizer
Hand-held nebulizers deliver medicines in the form of mist to add moisture and help control and repair your respiratory symptoms. The medicines and moisture will help control breathing problems like wheezing and help loosen lung secretions.
Initiate the machine and breathe in through a nebulizer mask. The medicine will go into your lungs as you take slow, deep breath for 20 to 30 minutes. It is easy and pleasant to breathe using the medicine into your lungs.

Why we use MESENCHYMAL STEM CELL (MSC)

Immunomodulatory Properties
MSCs can migrate to the sites of inflammation and hold potent of immunomodulatory and anti-inflammatory effects through cell and cell interactions between MSCs and lymphocytes or production of soluble factors. Therefore, the ability to promote tissue regeneration and improve overall lungs function are inevitable.

Paracrine Effect
Paracrine effects mean the need to receive the appropriate signals to initiate the regeneration and repair. MSCs also have anti-inflammatory and paracrine properties to reduce damage and to support tissue regeneration, constituting a promising cell-based treatment strategy for the repair of damaged alveolar tissue in emphysema.

Self-renewal & Regeneration
Stem cells are a population of undifferentiated cells characterized by the ability to extensively proliferate (self-renewal), MSCs have a high capacity for self renewal while maintaining multipotency. MSCs provide self-renew and differentiate into renew tissues that’s will help in enormous therapeutic potential for tissue repair.

Antimicrobial & Antifibrotic
Mesenchymal stem cells (MSCs) are able to modulate proliferation, activation, and effector function of all immune cells that play an important role in the pathogenesis of acute and chronic inflammatory lung diseases. The antimicrobial and antifibrotic properties in MSCs can improve wound healing and suppress inflammatory immune responses.
Source: C. Randall Harrell et al. 2019; Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives

Lung are FRAGILE
The adult lung is one of the few organs that has a direct interface with the outside environment. The airways of lung are lined with highly specialized cell types that are the target of airborne toxicants and injury. The epithelial cells that line the airways are constantly exposed to potential toxic agents and pathogens. Therefore, it must be able to respond quickly and effectively to recover the cellular damage.

Respiratory Inflammation
Inflammation is the result of the lung infection, trauma, and hypersensitivity caused by pathogens, airborne irritants, hazardous pollutants, toxins, and allergens. Pathogen-associated molecular patterns (PAMPs) expressed on the lung infiltrated microbes, as well as damage-associated molecular patterns (DAMPs) and alarmins, released from the injured lung parenchymal cells, activate residential macrophages which produce a large amount of inflammatory chemokines and cytokines, attract circulating immune cells in the lungs, and initiate inflammation.

PROTECT Your Lung
Your lungs, just like your heart, joints, and other parts of your body, age with time. They can become less flexible and lose their strength, which make it difficult to breathe.
superNEB can help looses mucus in your lungs so that you can breathe better, and increase your lung capacity.
MSC in immune activation and subsequent recruitment of monocytes in suppressing airway hyper responsiveness and airway inflammation.



mantra –
It is really a great product! Helps rejuvenate myself and I feel fresher